PPT - Non-enzymatic rates PowerPoint Presentation, free ... from image1.slideserve.com Waals surface revealed similar electronic structures of inhibitor and transition state because of the common protonation at n7, which is not present in the substrate hiv protease inhibitor. Discussion of transition state theory and the use of transition state analogs as enzyme inhibitors. A number of borinic and boronic acids have been found to inhibit acetylcholinesterase with k sub i values in the um range.
Transition state analogs are competitive inhibitors.
Transition state analogs consist of similar shape of the transition state of substrate. What kind of inhibitor is a transition state analog usually classified as? Transition state analogs consist of similar shape of the transition state of substrate. O competitive inhibitors o noncompetitive inhibitors.
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